Older Cancer Patients during the COVID-19 Epidemic: Practice Proposal of the International Geriatric Radiotherapy Group.
Identifieur interne : 000A30 ( Main/Exploration ); précédent : 000A29; suivant : 000A31Older Cancer Patients during the COVID-19 Epidemic: Practice Proposal of the International Geriatric Radiotherapy Group.
Auteurs : Nam P. Nguyen [États-Unis] ; Vincent Vinh-Hung [France] ; Brigitta Baumert [Suisse] ; Alice Zamagni [Italie] ; Meritxell Arenas [Espagne] ; Micaela Motta [Italie] ; Pedro Carlos Lara [Espagne] ; Arthur Sun Myint [Royaume-Uni] ; Marta Bonet [Espagne] ; Tiberiu Popescu [Roumanie] ; Te Vuong [Canada] ; Gokula Kumar Appalanaido [Malaisie] ; Lurdes Trigo [Portugal] ; Ulf Karlsson [États-Unis] ; Juliette Thariat [France]Source :
- Cancers [ 2072-6694 ] ; 2020.
Abstract
The coronavirus disease 19 (COVID-19) pandemic is unprecedented as it reached all countries in the world within a record short period of time. Even though COVID-19 infection may be just severe in any adults, older adults (65-year-old or older) may experience a higher mortality rate. Among those affected, cancer patients may have a worse outcome compared to the general population because of their depressed immune status. As the health resources of most countries are limited, clinicians may face painful decisions about which patients to save if they require artificial ventilation. Cancer patients, especially the older ones, may be denied supportive care because of their shorter life expectancy. Thus, special considerations should be taken to prevent infection of older cancer patients and to provide them with adequate social support during their cancer treatment. The following proposal was reached: (1) Education of health care providers about the special needs of older cancer patients and their risks of infection. (2) Special consideration such as surgical masks and separate scheduling should be made to protect them from being infected. (3) Social services such as patient navigators should be provided to ensure adequate medical supply, food, and daily transportation to cancer centers. (4) Close monitoring through phone calls, telecommunication to ensure social distancing and psychological support from patient family to prevent anxiety and depression. (5) Shorter course of radiotherapy by use of hypofractionation where possible to decrease the needs for daily transportation and exposure to infection. (6) Enrollment of older cancer patients in clinical trials for potential antiviral medications if infection does occur. (7) Home health care telemedicine may be an effective strategy for older cancer patients with COVID-19 infection to avoid hospital admission when health care resources become restricted. (8) For selected patients, immunotherapy and targeted therapy may become the systemic therapy of choice for older cancer patients and need to be tested in clinical trials.
DOI: 10.3390/cancers12051287
PubMed: 32438703
PubMed Central: PMC7281232
Affiliations:
- Canada, Espagne, France, Italie, Malaisie, Portugal, Roumanie, Royaume-Uni, Suisse, États-Unis
- Basse-Normandie, Canaries, Catalogne, District de Columbia, Martinique, Québec, Région Normandie
- Caen, Fort-de-France, Montréal
- Université McGill
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Older Cancer Patients during the COVID-19 Epidemic: Practice Proposal of the International Geriatric Radiotherapy Group.</title><author><name sortKey="Nguyen, Nam P" sort="Nguyen, Nam P" uniqKey="Nguyen N" first="Nam P" last="Nguyen">Nam P. Nguyen</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Howard University, Washington, DC 20060, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Howard University, Washington, DC 20060</wicri:regionArea><placeName><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Vinh Hung, Vincent" sort="Vinh Hung, Vincent" uniqKey="Vinh Hung V" first="Vincent" last="Vinh-Hung">Vincent Vinh-Hung</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, University Hospital of Martinique, 97200 Fort-de-France, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, University Hospital of Martinique, 97200 Fort-de-France</wicri:regionArea><placeName><region type="region" nuts="2">Martinique</region><settlement type="city">Fort-de-France</settlement></placeName></affiliation></author><author><name sortKey="Baumert, Brigitta" sort="Baumert, Brigitta" uniqKey="Baumert B" first="Brigitta" last="Baumert">Brigitta Baumert</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiation Oncology, Cantonal Hospital Graubuenden, 7000 Chur, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Radiation Oncology, Cantonal Hospital Graubuenden, 7000 Chur</wicri:regionArea><wicri:noRegion>7000 Chur</wicri:noRegion></affiliation></author><author><name sortKey="Zamagni, Alice" sort="Zamagni, Alice" uniqKey="Zamagni A" first="Alice" last="Zamagni">Alice Zamagni</name><affiliation wicri:level="1"><nlm:affiliation>Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna</wicri:regionArea><wicri:noRegion>40138 Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Arenas, Meritxell" sort="Arenas, Meritxell" uniqKey="Arenas M" first="Meritxell" last="Arenas">Meritxell Arenas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Sant Joan de Reus University, University Rovira I Virgili, 43201 Tarragona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation Oncology, Sant Joan de Reus University, University Rovira I Virgili, 43201 Tarragona</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Motta, Micaela" sort="Motta, Micaela" uniqKey="Motta M" first="Micaela" last="Motta">Micaela Motta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Hospital Papa Giovanni XXIII, 24127 Bergamo, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Radiation Oncology, Hospital Papa Giovanni XXIII, 24127 Bergamo</wicri:regionArea><wicri:noRegion>24127 Bergamo</wicri:noRegion></affiliation></author><author><name sortKey="Lara, Pedro Carlos" sort="Lara, Pedro Carlos" uniqKey="Lara P" first="Pedro Carlos" last="Lara">Pedro Carlos Lara</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Fernando Pessoa Canarias Las Palmas University, 35001 Las Palmas, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation Oncology, Fernando Pessoa Canarias Las Palmas University, 35001 Las Palmas</wicri:regionArea><placeName><region nuts="2" type="communauté">Canaries</region></placeName></affiliation></author><author><name sortKey="Myint, Arthur Sun" sort="Myint, Arthur Sun" uniqKey="Myint A" first="Arthur Sun" last="Myint">Arthur Sun Myint</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Clatterbridge Cancer Center, Liverpool CH63 4JY, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Radiation Oncology, Clatterbridge Cancer Center, Liverpool CH63 4JY</wicri:regionArea><wicri:noRegion>Liverpool CH63 4JY</wicri:noRegion></affiliation></author><author><name sortKey="Bonet, Marta" sort="Bonet, Marta" uniqKey="Bonet M" first="Marta" last="Bonet">Marta Bonet</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Arnau de Vilanova University Hospital, 25198 Lleida, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation Oncology, Arnau de Vilanova University Hospital, 25198 Lleida</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Popescu, Tiberiu" sort="Popescu, Tiberiu" uniqKey="Popescu T" first="Tiberiu" last="Popescu">Tiberiu Popescu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Prof. Dr. Ion Chricuta Oncology Institute, 400015 Cluj-Napoca, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Department of Radiation Oncology, Prof. Dr. Ion Chricuta Oncology Institute, 400015 Cluj-Napoca</wicri:regionArea><wicri:noRegion>400015 Cluj-Napoca</wicri:noRegion></affiliation></author><author><name sortKey="Vuong, Te" sort="Vuong, Te" uniqKey="Vuong T" first="Te" last="Vuong">Te Vuong</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiation Oncology, McGill University, Jewish General Hospital, Montreal, QC H3T1E2, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Radiation Oncology, McGill University, Jewish General Hospital, Montreal, QC H3T1E2</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Appalanaido, Gokula Kumar" sort="Appalanaido, Gokula Kumar" uniqKey="Appalanaido G" first="Gokula Kumar" last="Appalanaido">Gokula Kumar Appalanaido</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, AMDI, Universiti Sains Malaysia, Penang 13200, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Radiation Oncology, AMDI, Universiti Sains Malaysia, Penang 13200</wicri:regionArea><wicri:noRegion>Penang 13200</wicri:noRegion></affiliation></author><author><name sortKey="Trigo, Lurdes" sort="Trigo, Lurdes" uniqKey="Trigo L" first="Lurdes" last="Trigo">Lurdes Trigo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Instituto Portugues de Oncologia do Porto Francisco Martins Porto E.P.E, 4200-072 Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Radiation Oncology, Instituto Portugues de Oncologia do Porto Francisco Martins Porto E.P.E, 4200-072 Porto</wicri:regionArea><wicri:noRegion>4200-072 Porto</wicri:noRegion></affiliation></author><author><name sortKey="Karlsson, Ulf" sort="Karlsson, Ulf" uniqKey="Karlsson U" first="Ulf" last="Karlsson">Ulf Karlsson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, International Geriatric Group, Washington, DC 20001, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, International Geriatric Group, Washington, DC 20001</wicri:regionArea><placeName><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Thariat, Juliette" sort="Thariat, Juliette" uniqKey="Thariat J" first="Juliette" last="Thariat">Juliette Thariat</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, Baclesse Cancer Center, 14000 Caen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, Baclesse Cancer Center, 14000 Caen</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32438703</idno><idno type="pmid">32438703</idno><idno type="doi">10.3390/cancers12051287</idno><idno type="pmc">PMC7281232</idno><idno type="wicri:Area/Main/Corpus">001168</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001168</idno><idno type="wicri:Area/Main/Curation">001168</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001168</idno><idno type="wicri:Area/Main/Exploration">001168</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Older Cancer Patients during the COVID-19 Epidemic: Practice Proposal of the International Geriatric Radiotherapy Group.</title><author><name sortKey="Nguyen, Nam P" sort="Nguyen, Nam P" uniqKey="Nguyen N" first="Nam P" last="Nguyen">Nam P. Nguyen</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Howard University, Washington, DC 20060, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, Howard University, Washington, DC 20060</wicri:regionArea><placeName><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Vinh Hung, Vincent" sort="Vinh Hung, Vincent" uniqKey="Vinh Hung V" first="Vincent" last="Vinh-Hung">Vincent Vinh-Hung</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, University Hospital of Martinique, 97200 Fort-de-France, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, University Hospital of Martinique, 97200 Fort-de-France</wicri:regionArea><placeName><region type="region" nuts="2">Martinique</region><settlement type="city">Fort-de-France</settlement></placeName></affiliation></author><author><name sortKey="Baumert, Brigitta" sort="Baumert, Brigitta" uniqKey="Baumert B" first="Brigitta" last="Baumert">Brigitta Baumert</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiation Oncology, Cantonal Hospital Graubuenden, 7000 Chur, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Radiation Oncology, Cantonal Hospital Graubuenden, 7000 Chur</wicri:regionArea><wicri:noRegion>7000 Chur</wicri:noRegion></affiliation></author><author><name sortKey="Zamagni, Alice" sort="Zamagni, Alice" uniqKey="Zamagni A" first="Alice" last="Zamagni">Alice Zamagni</name><affiliation wicri:level="1"><nlm:affiliation>Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna</wicri:regionArea><wicri:noRegion>40138 Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Arenas, Meritxell" sort="Arenas, Meritxell" uniqKey="Arenas M" first="Meritxell" last="Arenas">Meritxell Arenas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Sant Joan de Reus University, University Rovira I Virgili, 43201 Tarragona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation Oncology, Sant Joan de Reus University, University Rovira I Virgili, 43201 Tarragona</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Motta, Micaela" sort="Motta, Micaela" uniqKey="Motta M" first="Micaela" last="Motta">Micaela Motta</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Hospital Papa Giovanni XXIII, 24127 Bergamo, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Radiation Oncology, Hospital Papa Giovanni XXIII, 24127 Bergamo</wicri:regionArea><wicri:noRegion>24127 Bergamo</wicri:noRegion></affiliation></author><author><name sortKey="Lara, Pedro Carlos" sort="Lara, Pedro Carlos" uniqKey="Lara P" first="Pedro Carlos" last="Lara">Pedro Carlos Lara</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Fernando Pessoa Canarias Las Palmas University, 35001 Las Palmas, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation Oncology, Fernando Pessoa Canarias Las Palmas University, 35001 Las Palmas</wicri:regionArea><placeName><region nuts="2" type="communauté">Canaries</region></placeName></affiliation></author><author><name sortKey="Myint, Arthur Sun" sort="Myint, Arthur Sun" uniqKey="Myint A" first="Arthur Sun" last="Myint">Arthur Sun Myint</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Clatterbridge Cancer Center, Liverpool CH63 4JY, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Radiation Oncology, Clatterbridge Cancer Center, Liverpool CH63 4JY</wicri:regionArea><wicri:noRegion>Liverpool CH63 4JY</wicri:noRegion></affiliation></author><author><name sortKey="Bonet, Marta" sort="Bonet, Marta" uniqKey="Bonet M" first="Marta" last="Bonet">Marta Bonet</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, Arnau de Vilanova University Hospital, 25198 Lleida, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Radiation Oncology, Arnau de Vilanova University Hospital, 25198 Lleida</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Popescu, Tiberiu" sort="Popescu, Tiberiu" uniqKey="Popescu T" first="Tiberiu" last="Popescu">Tiberiu Popescu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Prof. Dr. Ion Chricuta Oncology Institute, 400015 Cluj-Napoca, Romania.</nlm:affiliation><country xml:lang="fr">Roumanie</country><wicri:regionArea>Department of Radiation Oncology, Prof. Dr. Ion Chricuta Oncology Institute, 400015 Cluj-Napoca</wicri:regionArea><wicri:noRegion>400015 Cluj-Napoca</wicri:noRegion></affiliation></author><author><name sortKey="Vuong, Te" sort="Vuong, Te" uniqKey="Vuong T" first="Te" last="Vuong">Te Vuong</name><affiliation wicri:level="4"><nlm:affiliation>Department of Radiation Oncology, McGill University, Jewish General Hospital, Montreal, QC H3T1E2, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Radiation Oncology, McGill University, Jewish General Hospital, Montreal, QC H3T1E2</wicri:regionArea><orgName type="university">Université McGill</orgName><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Appalanaido, Gokula Kumar" sort="Appalanaido, Gokula Kumar" uniqKey="Appalanaido G" first="Gokula Kumar" last="Appalanaido">Gokula Kumar Appalanaido</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, AMDI, Universiti Sains Malaysia, Penang 13200, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Radiation Oncology, AMDI, Universiti Sains Malaysia, Penang 13200</wicri:regionArea><wicri:noRegion>Penang 13200</wicri:noRegion></affiliation></author><author><name sortKey="Trigo, Lurdes" sort="Trigo, Lurdes" uniqKey="Trigo L" first="Lurdes" last="Trigo">Lurdes Trigo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Radiation Oncology, Instituto Portugues de Oncologia do Porto Francisco Martins Porto E.P.E, 4200-072 Porto, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Department of Radiation Oncology, Instituto Portugues de Oncologia do Porto Francisco Martins Porto E.P.E, 4200-072 Porto</wicri:regionArea><wicri:noRegion>4200-072 Porto</wicri:noRegion></affiliation></author><author><name sortKey="Karlsson, Ulf" sort="Karlsson, Ulf" uniqKey="Karlsson U" first="Ulf" last="Karlsson">Ulf Karlsson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Radiation Oncology, International Geriatric Group, Washington, DC 20001, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiation Oncology, International Geriatric Group, Washington, DC 20001</wicri:regionArea><placeName><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Thariat, Juliette" sort="Thariat, Juliette" uniqKey="Thariat J" first="Juliette" last="Thariat">Juliette Thariat</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiation Oncology, Baclesse Cancer Center, 14000 Caen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Radiation Oncology, Baclesse Cancer Center, 14000 Caen</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author></analytic><series><title level="j">Cancers</title><idno type="ISSN">2072-6694</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The coronavirus disease 19 (COVID-19) pandemic is unprecedented as it reached all countries in the world within a record short period of time. Even though COVID-19 infection may be just severe in any adults, older adults (65-year-old or older) may experience a higher mortality rate. Among those affected, cancer patients may have a worse outcome compared to the general population because of their depressed immune status. As the health resources of most countries are limited, clinicians may face painful decisions about which patients to save if they require artificial ventilation. Cancer patients, especially the older ones, may be denied supportive care because of their shorter life expectancy. Thus, special considerations should be taken to prevent infection of older cancer patients and to provide them with adequate social support during their cancer treatment. The following proposal was reached: (1) Education of health care providers about the special needs of older cancer patients and their risks of infection. (2) Special consideration such as surgical masks and separate scheduling should be made to protect them from being infected. (3) Social services such as patient navigators should be provided to ensure adequate medical supply, food, and daily transportation to cancer centers. (4) Close monitoring through phone calls, telecommunication to ensure social distancing and psychological support from patient family to prevent anxiety and depression. (5) Shorter course of radiotherapy by use of hypofractionation where possible to decrease the needs for daily transportation and exposure to infection. (6) Enrollment of older cancer patients in clinical trials for potential antiviral medications if infection does occur. (7) Home health care telemedicine may be an effective strategy for older cancer patients with COVID-19 infection to avoid hospital admission when health care resources become restricted. (8) For selected patients, immunotherapy and targeted therapy may become the systemic therapy of choice for older cancer patients and need to be tested in clinical trials.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32438703</PMID><DateRevised><Year>2020</Year><Month>06</Month><Day>16</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">2072-6694</ISSN><JournalIssue CitedMedium="Print"><Volume>12</Volume><Issue>5</Issue><PubDate><Year>2020</Year><Month>May</Month><Day>19</Day></PubDate></JournalIssue><Title>Cancers</Title><ISOAbbreviation>Cancers (Basel)</ISOAbbreviation></Journal><ArticleTitle>Older Cancer Patients during the COVID-19 Epidemic: Practice Proposal of the International Geriatric Radiotherapy Group.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E1287</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/cancers12051287</ELocationID><Abstract><AbstractText>The coronavirus disease 19 (COVID-19) pandemic is unprecedented as it reached all countries in the world within a record short period of time. Even though COVID-19 infection may be just severe in any adults, older adults (65-year-old or older) may experience a higher mortality rate. Among those affected, cancer patients may have a worse outcome compared to the general population because of their depressed immune status. As the health resources of most countries are limited, clinicians may face painful decisions about which patients to save if they require artificial ventilation. Cancer patients, especially the older ones, may be denied supportive care because of their shorter life expectancy. Thus, special considerations should be taken to prevent infection of older cancer patients and to provide them with adequate social support during their cancer treatment. The following proposal was reached: (1) Education of health care providers about the special needs of older cancer patients and their risks of infection. (2) Special consideration such as surgical masks and separate scheduling should be made to protect them from being infected. (3) Social services such as patient navigators should be provided to ensure adequate medical supply, food, and daily transportation to cancer centers. (4) Close monitoring through phone calls, telecommunication to ensure social distancing and psychological support from patient family to prevent anxiety and depression. (5) Shorter course of radiotherapy by use of hypofractionation where possible to decrease the needs for daily transportation and exposure to infection. (6) Enrollment of older cancer patients in clinical trials for potential antiviral medications if infection does occur. (7) Home health care telemedicine may be an effective strategy for older cancer patients with COVID-19 infection to avoid hospital admission when health care resources become restricted. (8) For selected patients, immunotherapy and targeted therapy may become the systemic therapy of choice for older cancer patients and need to be tested in clinical trials.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nguyen</LastName><ForeName>Nam P</ForeName><Initials>NP</Initials><Identifier Source="ORCID">0000-0001-5106-6665</Identifier><AffiliationInfo><Affiliation>Department of Radiation Oncology, Howard University, Washington, DC 20060, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vinh-Hung</LastName><ForeName>Vincent</ForeName><Initials>V</Initials><Identifier Source="ORCID">0000-0002-6403-6120</Identifier><AffiliationInfo><Affiliation>Department of Radiation Oncology, University Hospital of Martinique, 97200 Fort-de-France, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baumert</LastName><ForeName>Brigitta</ForeName><Initials>B</Initials><Identifier Source="ORCID">0000-0001-8871-4654</Identifier><AffiliationInfo><Affiliation>Institute of Radiation Oncology, Cantonal Hospital Graubuenden, 7000 Chur, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zamagni</LastName><ForeName>Alice</ForeName><Initials>A</Initials><Identifier Source="ORCID">0000-0001-8942-793X</Identifier><AffiliationInfo><Affiliation>Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arenas</LastName><ForeName>Meritxell</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0003-0815-2570</Identifier><AffiliationInfo><Affiliation>Department of Radiation Oncology, Sant Joan de Reus University, University Rovira I Virgili, 43201 Tarragona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Motta</LastName><ForeName>Micaela</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Hospital Papa Giovanni XXIII, 24127 Bergamo, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lara</LastName><ForeName>Pedro Carlos</ForeName><Initials>PC</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Fernando Pessoa Canarias Las Palmas University, 35001 Las Palmas, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Myint</LastName><ForeName>Arthur Sun</ForeName><Initials>AS</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Clatterbridge Cancer Center, Liverpool CH63 4JY, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonet</LastName><ForeName>Marta</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Arnau de Vilanova University Hospital, 25198 Lleida, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Popescu</LastName><ForeName>Tiberiu</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Prof. Dr. Ion Chricuta Oncology Institute, 400015 Cluj-Napoca, Romania.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vuong</LastName><ForeName>Te</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, McGill University, Jewish General Hospital, Montreal, QC H3T1E2, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Appalanaido</LastName><ForeName>Gokula Kumar</ForeName><Initials>GK</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, AMDI, Universiti Sains Malaysia, Penang 13200, Malaysia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Trigo</LastName><ForeName>Lurdes</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Instituto Portugues de Oncologia do Porto Francisco Martins Porto E.P.E, 4200-072 Porto, Portugal.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karlsson</LastName><ForeName>Ulf</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, International Geriatric Group, Washington, DC 20001, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thariat</LastName><ForeName>Juliette</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Baclesse Cancer Center, 14000 Caen, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>05</Month><Day>19</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Cancers (Basel)</MedlineTA><NlmUniqueID>101526829</NlmUniqueID><ISSNLinking>2072-6694</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">cancer patients</Keyword><Keyword MajorTopicYN="N">corona virus 19</Keyword><Keyword MajorTopicYN="N">epidemic</Keyword><Keyword MajorTopicYN="N">older</Keyword><Keyword MajorTopicYN="N">treatment</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>04</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>05</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>05</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>5</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>5</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>5</Month><Day>23</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32438703</ArticleId><ArticleId IdType="pii">cancers12051287</ArticleId><ArticleId IdType="doi">10.3390/cancers12051287</ArticleId><ArticleId IdType="pmc">PMC7281232</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Medicine (Baltimore). 2016 Oct;95(43):e5212</Citation><ArticleIdList><ArticleId IdType="pubmed">27787380</ArticleId></ArticleIdList></Reference><Reference><Citation>Drugs Aging. 2019 Oct;36(10):927-938</Citation><ArticleIdList><ArticleId IdType="pubmed">31317421</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Med. 1994 Aug 15;97(2A):28-33</Citation><ArticleIdList><ArticleId IdType="pubmed">8059798</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Antimicrob Agents. 2020 Mar 20;:105949</Citation><ArticleIdList><ArticleId IdType="pubmed">32205204</ArticleId></ArticleIdList></Reference><Reference><Citation>Lung Cancer. 2012 Feb;75(2):255-60</Citation><ArticleIdList><ArticleId IdType="pubmed">21816502</ArticleId></ArticleIdList></Reference><Reference><Citation>Gerontologist. 2010 Aug;50(4):443-50</Citation><ArticleIdList><ArticleId IdType="pubmed">20145017</ArticleId></ArticleIdList></Reference><Reference><Citation>Psychooncology. 2015 Nov;24(11):1521-8</Citation><ArticleIdList><ArticleId IdType="pubmed">25914244</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncol Lett. 2017 Aug;14(2):1568-1580</Citation><ArticleIdList><ArticleId IdType="pubmed">28789381</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(4):e35797</Citation><ArticleIdList><ArticleId IdType="pubmed">22563403</ArticleId></ArticleIdList></Reference><Reference><Citation>J Womens Health (Larchmt). 2013 Jun;22(6):507-17</Citation><ArticleIdList><ArticleId IdType="pubmed">23672296</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncol Lett. 2016 Jan;11(1):3-8</Citation><ArticleIdList><ArticleId IdType="pubmed">26870160</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 May 6;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32374370</ArticleId></ArticleIdList></Reference><Reference><Citation>Gerontologist. 2016 Jun;56(3):432-43</Citation><ArticleIdList><ArticleId IdType="pubmed">25601389</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2017 Jul 18;12(7):e0181312</Citation><ArticleIdList><ArticleId IdType="pubmed">28719660</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Environ Res Public Health. 2016 Dec 06;13(12):</Citation><ArticleIdList><ArticleId IdType="pubmed">27929452</ArticleId></ArticleIdList></Reference><Reference><Citation>Cancers (Basel). 2019 Mar 16;11(3):</Citation><ArticleIdList><ArticleId IdType="pubmed">30884827</ArticleId></ArticleIdList></Reference><Reference><Citation>CA Cancer J Clin. 2017 Sep;67(5):362-377</Citation><ArticleIdList><ArticleId IdType="pubmed">28731537</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gastrointest Oncol. 2014 Jun;5(3):212-7</Citation><ArticleIdList><ArticleId IdType="pubmed">24982769</ArticleId></ArticleIdList></Reference><Reference><Citation>J Natl Cancer Inst Monogr. 2004;(32):57-71</Citation><ArticleIdList><ArticleId IdType="pubmed">15263042</ArticleId></ArticleIdList></Reference><Reference><Citation>Cochrane Database Syst Rev. 2016 Sep 01;9:CD007491</Citation><ArticleIdList><ArticleId IdType="pubmed">27583824</ArticleId></ArticleIdList></Reference><Reference><Citation>Expert Opin Biol Ther. 2019 Mar;19(3):225-232</Citation><ArticleIdList><ArticleId IdType="pubmed">30657338</ArticleId></ArticleIdList></Reference><Reference><Citation>J Geriatr Oncol. 2017 Nov;8(6):437-442</Citation><ArticleIdList><ArticleId IdType="pubmed">28888556</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Commun. 2019 Feb 18;10(1):814</Citation><ArticleIdList><ArticleId IdType="pubmed">30778080</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 Apr 6;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32250385</ArticleId></ArticleIdList></Reference><Reference><Citation>J Community Health. 2013 Oct;38(5):976-93</Citation><ArticleIdList><ArticleId IdType="pubmed">23543372</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Oncol. 2014 Aug 20;32(24):2635-46</Citation><ArticleIdList><ArticleId IdType="pubmed">25071113</ArticleId></ArticleIdList></Reference><Reference><Citation>AIDS Patient Care STDS. 2014 Feb;28(2):82-90</Citation><ArticleIdList><ArticleId IdType="pubmed">24517539</ArticleId></ArticleIdList></Reference><Reference><Citation>J Glob Oncol. 2019 Jul;5:1-5</Citation><ArticleIdList><ArticleId IdType="pubmed">31348737</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA Oncol. 2019 May 1;5(5):644-652</Citation><ArticleIdList><ArticleId IdType="pubmed">30946436</ArticleId></ArticleIdList></Reference><Reference><Citation>Cochrane Database Syst Rev. 2015 Sep 07;(9):CD002098</Citation><ArticleIdList><ArticleId IdType="pubmed">26343551</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Internet Res. 2019 Oct 29;21(10):e14360</Citation><ArticleIdList><ArticleId IdType="pubmed">31663861</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Prev Med. 2007 Sep;33(3):222-49</Citation><ArticleIdList><ArticleId IdType="pubmed">17826584</ArticleId></ArticleIdList></Reference><Reference><Citation>CA Cancer J Clin. 2011 Jul-Aug;61(4):237-49</Citation><ArticleIdList><ArticleId IdType="pubmed">21659419</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Dis (Lond). 2019 Jul;51(7):502-509</Citation><ArticleIdList><ArticleId IdType="pubmed">31081422</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Oncol. 2018 Oct 10;36(29):2943-2949</Citation><ArticleIdList><ArticleId IdType="pubmed">30106637</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Oncol. 2020 Mar;21(3):335-337</Citation><ArticleIdList><ArticleId IdType="pubmed">32066541</ArticleId></ArticleIdList></Reference><Reference><Citation>Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):145-151</Citation><ArticleIdList><ArticleId IdType="pubmed">32064853</ArticleId></ArticleIdList></Reference><Reference><Citation>J R Soc Med. 2013 Apr;106(4):130-42</Citation><ArticleIdList><ArticleId IdType="pubmed">23564897</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Oncol. 2019 Mar;20(3):352-360</Citation><ArticleIdList><ArticleId IdType="pubmed">30711522</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncologist. 2019 Sep;24(9):1195-1200</Citation><ArticleIdList><ArticleId IdType="pubmed">30498134</ArticleId></ArticleIdList></Reference><Reference><Citation>ESMO Open. 2018 Jul 25;3(5):e000332</Citation><ArticleIdList><ArticleId IdType="pubmed">30094065</ArticleId></ArticleIdList></Reference><Reference><Citation>Br J Surg. 2020 Apr;107(5):509-518</Citation><ArticleIdList><ArticleId IdType="pubmed">32100297</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 Mar 12;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32163102</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 Feb 21;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32083643</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Microbiol. 2003 Sep 21;3:20</Citation><ArticleIdList><ArticleId IdType="pubmed">14499001</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Geriatr. 2015 Jul 09;15:79</Citation><ArticleIdList><ArticleId IdType="pubmed">26156892</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect. 2020 Jun;80(6):e14-e18</Citation><ArticleIdList><ArticleId IdType="pubmed">32171866</ArticleId></ArticleIdList></Reference><Reference><Citation>J Thorac Oncol. 2020 May;15(5):700-704</Citation><ArticleIdList><ArticleId IdType="pubmed">32114094</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Canada</li><li>Espagne</li><li>France</li><li>Italie</li><li>Malaisie</li><li>Portugal</li><li>Roumanie</li><li>Royaume-Uni</li><li>Suisse</li><li>États-Unis</li></country><region><li>Basse-Normandie</li><li>Canaries</li><li>Catalogne</li><li>District de Columbia</li><li>Martinique</li><li>Québec</li><li>Région Normandie</li></region><settlement><li>Caen</li><li>Fort-de-France</li><li>Montréal</li></settlement><orgName><li>Université McGill</li></orgName></list><tree><country name="États-Unis"><region name="District de Columbia"><name sortKey="Nguyen, Nam P" sort="Nguyen, Nam P" uniqKey="Nguyen N" first="Nam P" last="Nguyen">Nam P. Nguyen</name></region><name sortKey="Karlsson, Ulf" sort="Karlsson, Ulf" uniqKey="Karlsson U" first="Ulf" last="Karlsson">Ulf Karlsson</name></country><country name="France"><region name="Martinique"><name sortKey="Vinh Hung, Vincent" sort="Vinh Hung, Vincent" uniqKey="Vinh Hung V" first="Vincent" last="Vinh-Hung">Vincent Vinh-Hung</name></region><name sortKey="Thariat, Juliette" sort="Thariat, Juliette" uniqKey="Thariat J" first="Juliette" last="Thariat">Juliette Thariat</name></country><country name="Suisse"><noRegion><name sortKey="Baumert, Brigitta" sort="Baumert, Brigitta" uniqKey="Baumert B" first="Brigitta" last="Baumert">Brigitta Baumert</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Zamagni, Alice" sort="Zamagni, Alice" uniqKey="Zamagni A" first="Alice" last="Zamagni">Alice Zamagni</name></noRegion><name sortKey="Motta, Micaela" sort="Motta, Micaela" uniqKey="Motta M" first="Micaela" last="Motta">Micaela Motta</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Arenas, Meritxell" sort="Arenas, Meritxell" uniqKey="Arenas M" first="Meritxell" last="Arenas">Meritxell Arenas</name></region><name sortKey="Bonet, Marta" sort="Bonet, Marta" uniqKey="Bonet M" first="Marta" last="Bonet">Marta Bonet</name><name sortKey="Lara, Pedro Carlos" sort="Lara, Pedro Carlos" uniqKey="Lara P" first="Pedro Carlos" last="Lara">Pedro Carlos Lara</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Myint, Arthur Sun" sort="Myint, Arthur Sun" uniqKey="Myint A" first="Arthur Sun" last="Myint">Arthur Sun Myint</name></noRegion></country><country name="Roumanie"><noRegion><name sortKey="Popescu, Tiberiu" sort="Popescu, Tiberiu" uniqKey="Popescu T" first="Tiberiu" last="Popescu">Tiberiu Popescu</name></noRegion></country><country name="Canada"><region name="Québec"><name sortKey="Vuong, Te" sort="Vuong, Te" uniqKey="Vuong T" first="Te" last="Vuong">Te Vuong</name></region></country><country name="Malaisie"><noRegion><name sortKey="Appalanaido, Gokula Kumar" sort="Appalanaido, Gokula Kumar" uniqKey="Appalanaido G" first="Gokula Kumar" last="Appalanaido">Gokula Kumar Appalanaido</name></noRegion></country><country name="Portugal"><noRegion><name sortKey="Trigo, Lurdes" sort="Trigo, Lurdes" uniqKey="Trigo L" first="Lurdes" last="Trigo">Lurdes Trigo</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidFranceV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A30 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A30 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidFranceV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32438703
|texte= Older Cancer Patients during the COVID-19 Epidemic: Practice Proposal of the International Geriatric Radiotherapy Group.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32438703" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidFranceV1
| This area was generated with Dilib version V0.6.37. |  |